Why is clonidine sedating social networking dating bisexuals
Study population: All patients 18 years old, intubated mechanically ventilated and sedated at inclusion.
Intervention: Clonidine infusion of 0,25 mcg/kg/h added to the standard sedation regimen. Main study parameters/endpoints: The main study parameter is the total number of awake and delirium-free observation periods the first 7 days after randomisation.
To help control his aggression and impulsivity, his doctor prescribed Clonidine.
I give it to him only when his behavior is out of control, and generally 0.05mg is sufficient to calm him.
Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. Oral clonidine may be a safe and effective sedative in combination with morphine and lorazepam for young children with single-organ, respiratory failure.This agent may also exhibit opioid and benzodiazepine sparing effects in this patient group. ABSTRACT: In intensive care units, the precise administration of sedatives and analgesics is crucial in order to avoid under- or over sedation and for appropriate pain control.We aimed to document our experience with oral clonidine when used as a sedative in combination with intravenous morphine and lorazepam in a group of mechanically ventilated children with single-organ, respiratory failure. Twenty-four children were enrolled (median age 3 months) of whom ten were excluded (six due to extubation before 72 h, three sedation failures, one protocol violation).In particular, our objectives were to establish the relationship between oral dose, plasma concentration, and sedative effect, and second, to document the side-effect profile. Plasma clonidine was measured using gas chromatography mass spectrometry, and sedation assessed using the COMFORT score.